Larry Winfield.com: Sundown Lounge - Maproom Archives
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Map Room Archive: Shows 31 - 45






From
Sundown Lounge No. 45



NASA's ISS Website

Motorcycle Airbag


Motorcyclists have long been the most vulnerable road users because they do not have an effective barrier between themselves and other objects in an accident. A flurry of activity in motorcycle protective gear could change things. Honda recently showed its first air-bag on a motorcycle and manufacturers are developing a cross between the airbag and a protective jacket designed to protect the motorcycle rider's neck and spine in the event of an accident

One of the first to market with the new design is Hit-Air which sells a range of jackets and vests featuring airbag technology designed to keep riders safe and comfortable in a wide range of driving and climatic conditions. The jackets are already in use by police departments in Brazil, Italy, Japan and Spain and appear to offer significantly greater protection than a normal jacket. The inflatable vests are finding application in many other potentially dangerous activities such as horseriding and power sports.

All Hit-Air jackets and vests incorporate the "Hit-Air" airbag safety system designed to protect the rider's neck, spine and vital organs in the event of a fall or collision. The "Hit Air" jacket uses CE certified armor to protect the shoulders, elbows and the spine but most importantly, the "Hit Air" jacket also incorporates an air cushion system. In the event of an accident and a rider is thrown from the motorcycle, the air cushion instantly inflates (within 1/2 second) to protect the rider's body.

Activation is simple and automatic. A coiled wire is attached to both the motorcycle and the jacket. Once the rider and the motorcycle are separated, the coiled wire pulls a "key" out of a gas release system and inert gas inflates the air cushion. The inflated jacket provides the necessary impact protection. After a few seconds the gas is automatically released through the gas release valve. Once the gas is released a new cartridge can be installed and the jacket is ready for reuse.


Obesity Vaccine

It is one of the world’s greatest ironies that while a billion of the planet’s citizens are quite literally starving, another billion are eating themselves to death. According to the World Health Organization, more than one billion people worldwide are overweight and of these at least 300 million are clinically obese.

The cost of obesity in terms of morbidity, mortality and medical expenditure is enormous. WHO reports that developed countries spend 2-7% of total health care costs on obesity-related problems. Which is why the announcement this week from a small Swiss biotechnology company has such massive ramifications. The company is beginning trials of a drug which it believes will not only suppress the appetite and assist in losing weight, but keep the weight off in the long term. Immunodrug candidate CYT009-GhrQb is effectively a therapeutic vaccine for the treatment of obesity.

The clinical study will include 112 obese individuals with a body mass index (BMI) between 30 and 35, and is designed to evaluate safety, tolerability, and exploratory efficacy of the vaccine. The multicentre study is being conducted according to a randomised, double-blind and placebo controlled design. Three different dose regimens of the vaccine will be compared against placebo.

The treatment period of six months per individual will be followed by monitoring of safety and efficacy over a further six months. During the treatment, all participants will receive professional counselling to achieve a change in eating habits and improve physical activity. Efficacy of the vaccine will be determined by measurement of body weight. First results of the study are expected in the second half of 2006...






Finally there is an innovative answer that not only provides a practical solution to book storage but is guaranteed to get people talking.

Sticklebook has invented the world's first invisible shelving system that creates the illusion of a line of books hanging unsupported on the wall. It can be used absolutely anywhere and for any situation.

Sticklebook's innovative design is comprised of an aluminium extrusion which acts as a bracket and polypropylene combed strip that grips the cover and pages of paperback books. The shelf is screwed onto the wall which itself helps support the weight of the book and is an integral part of the design. They claim it is totally secure and fall-proof.



PNAC Cliff Notes

(This is a summary of the original 90-page document...)

Many thanks to Sam Wenger for preparing this summary.

These are talking points concerning this PNAC plan which George W. Bush has apparently adopted as a blueprint for his administration’s foreign policy. An original copy of this PNAC document can be obtained from: www.newamericancentury.org It consists of 90 pages. What does this (PNAC) document reveal about the following topics and ideas?

1. Weapons of Mass Destruction. As for Iraq’s alleged "weapons of mass destruction", these were dismissed, in so many words, as a convenient excuse, which it is. "While the unresolved conflict with Iraq provides the immediate justification," it says, "the need for a substantial American force presence in the Gulf transcends the issue of the regime of Saddam Hussein." How has this grand strategy been implemented? A series of articles in the Washington Post, co-authored by Bob Woodward of Watergate fame and based on long interviews with senior members of the Bush administration, reveals how September 11 was manipulated.

2. Terrorism. One should note that on September 12, 2001, without any evidence of who the hijackers were, Donald Rumsfeld demanded that the United States attack Iraq. According to Woodward, Rumsfeld told a cabinet meeting that Iraq should be "a principal target of the first round in the war against terrorism". Iraq was temporarily spared only because Colin Powell, the secretary of state, persuaded Bush that "public opinion has to be prepared before a move against Iraq is possible". Afghanistan was chosen as the softer option. If Jonathan Steele’s estimate in the Guardian is correct, some 20,000 people in Afghanistan paid the price of this debate with their lives.

3. Saddam Hassein. One of the PNAC group documents clearly shows that Bush and his most senior cabinet members had already planned an attack on Iraq before he took power in January 2001. In their plan entitled "Rebuilding American’s Defenses: Strategies, Forces and Resources for a New Century," reveals that the current members of Bush’s cabinet had already planned, before the 2000 presidential election, to take military control of the Gulf region whether Saddam Hussein is in power or not. "Even should Saddam pass from the scene," the plan says U.S. military bases in Saudi Arabia and Kuwait will remain, despite domestic opposition in the Gulf states to the permanent stationing of U.S. troops. Iran, it says, "may well prove as large a threat to U.S. interests as Iraq has." The 90-page PNAC document from September 2000 says: "The United States has for decades sought to play a more permanent role in Gulf regional security. While the unresolved conflict with Iraq provides the immediate justification, the need for a substantial American force presence in the Gulf transcends the issue of the regime of Saddam Hussein. The plan calls for Permanent Military Bases in Iraq to dominate the Middle East including neighboring Iran...

www.ecapc.org



From Geeknotes:

Daize Shayne has a glamour spread in the french magazine freesport, along with Heidi Klum and Giselle Bunchen. It's the May 5th edition, no. 92.




From
Sundown Lounge No. 44



NASA's ISS Website

April 28, 2006

International Space Station Status Report: SS06-021


The 13th crew of the International Space Station this week began unloading -- and sank its teeth into -- some of the more than 5,000 pounds of new supplies that arrived at the complex Wednesday.

The ISS Progress 21 cargo spacecraft, which launched from the Baikonur Cosmodrome in Kazakhstan on Monday, docked at the station Wednesday. The ship was the first supply shipment for Expedition 13 Commander Pavel Vinogradov and Flight Engineer Jeff Williams, who have been in space for almost a month.

The spacecraft brought fresh fruit and other foods, gifts from home, fuel, water, oxygen, spare parts and science gear. Two Progress cargo craft are now docked at the complex. Oxygen supplies from ISS Progress 20, which arrived in December, continue to be used to replenish the cabin air when required. The crew is loading that Progress with trash and unneeded equipment. The spacecraft will be jettisoned from the complex in mid-June.

Early in the week, Williams replaced a Remote Power Control Module, a type of circuit breaker, in the station's Destiny laboratory. The power control module had not been functioning for some time, and electricity for many lab systems had been delivered via an alternate path. To gain access to the worksite for replacement of the component, Williams had to disassemble and remove his sleeping compartment. Mission Control sequentially powered off many lab systems and lights to facilitate the replacement. Williams accomplished all the work ahead of schedule, and the new power control module has been functioning well.

Science activities aboard the station during the past week included work by Williams with the Capillary Flow Experiment, which is an investigation of fluid behavior in weightlessness that may assist in the design of future spacecraft. The crew members also completed urine collection and notes about their food consumption for an experiment studying the formation of kidney stones in weightlessness.

Vinogradov completed routine maintenance of the station's Elektron system. It was powered off much of the week and reactivated today. The Elektron provides oxygen for the cabin air from water.

Plans for next week include an engine firing to boost the station's altitude on Thursday, May 4; continued unloading of the newly arrived Progress vehicle; and periodic crew health checks.

The next station status report will be issued on Friday, May 5, or earlier if events warrant. For more about the crew's activities and station sighting opportunities, visit: http://www.nasa.gov/station


Hollywood Does Movie Mashups

By Niall McKay
02:00 AM May, 01, 2006


Hollywood has drafted a British VJ outfit to produce the first official movie mashup.

New Line Cinema commissioned Addictive TV, a British VJ duo, to mashup the new Antonio Banderas blockbuster Take The Lead to market to the iPod generation.

The Brit duo, known for bootleg movie remixes of titles like the Italian Job and James Bond were commissioned by New Line in a VJ faceoff with DJ 2nd Nature and Electric Method.

"It's the first time that a Hollywood studio has included a mix as part of its (marketing) package," said Graham Daniels, who runs Addictive TV with DJ Trolly.

The pair are no newcomers to mixing and mashing video. As a live act, they've been on the road VJing since 1992. Performing live, they blend film footage, video and audio clips using video and audio mixers, DVD turntables, laptop computers and video projectors. But the recent upswing in mashup culture is giving them a new lease of life. more...



Environmental DNA Damage
May Drive Human Mutation




Mutations drive evolution. Subtle changes in the pairing of the chemical letters of DNA--adenine, cytosine, guanine and thymine--produce new cells with different traits than their ancestors. The fundamental basis of such change is called a single nucleotide polymorphism, or a copying error in the long, chemical book of DNA. Now Japanese researchers have shown how environmentally damaged letters lead to transcription flaws and, ultimately, human diversity.

Ultraviolet light, environmental chemicals, even the by-products of normal cellular metabolism all conspire to continually assault the DNA of humans and every other living thing. Typically, they cause the four chemical precursors to undergo oxidation. For guanine, or G, its oxidized version is called 8-oxoG. When lurking in the area during DNA replication, it bonds with adenine and causes the latter to pair with thymine rather than with its correct partner, unoxidized guanine. This is a permanent change, or mutation.

Geneticist Yusaku Nakabeppu of Kyushu University and his colleagues studied the abundance of 8-oxoG in cellular cultures from four subjects, two men and two women. By fluorescently labeling monoclonal antibodies that attach to DNA sites where 8-oxoG has made its changes the researchers revealed that the oxidized guanine does not occur randomly throughout the chromosome but rather clusters in certain areas. more...


Semen makes you happy...

Semen makes you happy. That’s the remarkable conclusion of a study comparing women whose partners wear condoms with those whose partners don’t.

The study, which is bound to provoke controversy, showed that the women who were directly exposed to semen were less depressed. The researchers think this is because mood-altering hormones in semen are absorbed through the vagina. They say they have ruled out other explanations.

“I want to make it clear that we are not advocating that people abstain from using condoms,” says Gordon Gallup, the psychologist at the State University of New York who led the team. “Clearly an unwanted pregnancy or a sexually transmitted disease would more than offset any advantageous psychological effects of semen.” Suicide attempts

His team divided 293 female students into groups depending on how often their partners wore condoms, and assessed their happiness using the Beck Depression Inventory, a standard questionnaire for assessing mood. People who score over 17 are considered moderately depressed.

The team found that women whose partners never used condoms scored 8 on average, those who sometimes used them scored 10.5, those who usually used them scored 15 and those who always used them scored 11.3. Women who weren’t having sex at all scored 13.5. more...





From
Sundown Lounge No. 43



Tagging Air Force One


Last week an Internet video popped up that showed someone spraying graffiti on President Bush's jet. It looked so authentic that the Air Force wasn't immediately certain whether the plane had been targeted. It was a hoax, pulled off by a New York fashion company guy, Marc Ecko of Marc Ecko Enterprises. Did it make the evening news?

Here's the Quicktime movie...


Hubble Space Telescope is Sweet 16:


NASA and the European Space Agency have issued new high-resolution photos of the starburst Messier 82 galaxy. The images show the birth of hundreds of young stars at the core of the so-called Cigar Galaxy. If you click the hubble pic on the page, it'll take you to the ESA's Hubble site...

Jenna on the beach...

With summer just around the corner, now I can flash the pictures of Jenna Bush, who flashed a beach, and a couple photographers, a while back...

New Penicillin in Wallaby Milk

Scientists down under have discovered a bacteria-fighting compound 100 times more effective than penicillin - in wallaby milk. Researchers from the Victorian government's Department of Primary Industries discovered this compound - tagged AGG01 - while investigating the chemical properties of Tammar wallabies' breast milk to determine how their immune-deficient newborns built up resistance to bacteria while in the pouch.

They discovered that AGG01, was active against a wide variety of fungi and bacteria including a relative of the hospital superbug MRSA, or golden staph, ecoli, and Salmonella...


Is Technology Changing Our Brains?

Sometimes the House of Lords throws out speeches so interesting and radical, that you simply cannot imagine them being made in the Commons. One such came this week from the neuro-biologist Susan Greenfield. She asked a question that affects all of us, yet which I have never heard discussed by mainstream politicians: is technology changing our brains?

It is most striking when you watch children and young adults. This is not just the obvious ageing person's whinge because my kids can sort out computer or digital camera problems that baffle me. It is more about the way they absorb information and entertainment...




From
Sundown Lounge No. 42



Reasons to Love Open-Source DRM
From Eliot Van Buskirk's "Listening Post"


I acknowledge that the title of this column is strange. Aside from the fact that most savvy music listeners (justifiably) hate DRM, the very idea of using open-source software to enforce digital rights management runs counter to everything commonly assumed about the technology: that it needs to be secret, obscure, proprietary.

But open-source DRM is exactly what Sun Microsystems has proposed, with its DReaM initiative. Its goal is to promulgate an open-source architecture for digital rights management that would cut across devices, regardless of the manufacturer, and assign rights to individuals rather than gadgets...


Also From "Listening Post":

The Man Behind Scrambled Hackz


I saw a video the other day that really stood out from the rest of the links making the rounds.


It depicts a man demonstrating software that appears to parse what he's saying fast enough to reassemble the same words by pulling and reordering bits from a recorded Michael Jackson interview. The result: Jackson appears to speak the same sentence right back to him.

The man goes on to explain how the software behind this process works, and his video closes with a live performance of the software in which a performer appears to employ the beat-box method to control the playback of audio and video on a large video screen behind him, in front of what I can only imagine must be a dazzled crowd...


From Impact Lab:

Birch Bark


Imagine the treatment for some cancers growing in our forests. Or powerful drugs for herpes, HIV or liver disease. How about a natural source of biodegradable plastic, skin conditioner or mosquito repellent? Or maybe a nontoxic pesticide or fungicide for gardens?

Behold the birch tree, the noble Northland native that someday might serve as a medicine chest for the world.

A group of Duluth scientists is extracting a natural chemical from birch bark that appears to hold incredible potential for fighting diseases. It has been slow to develop, but the first commercial success may be near, part of a global shift to more natural-based compounds and chemicals...



No items for Sundown Lounge No. 41 -
It's Spring Break!


From
Sundown Lounge No. 40



Big Easy to Telcos: Stick It
From Wired.com and Associated Press 08:45 AM Apr, 04, 2006

A showdown may be looming over a free wireless internet network that New Orleans set up to boost recovery after Hurricane Katrina pummeled the city.

Calling the network vital to the city's economic comeback, New Orleans technology chief Greg Meffert is vowing to keep the system running as is, even if it means breaking a state law that permits its full operation only during emergencies.

He says he's ready to go to court, if necessary.

"If you can get to the net, you can do business," Meffert said.

The system, established with $1 million in donated equipment, made its debut last fall in the wake of the hurricane disaster. It's the first free wireless internet network owned and run by a major city.


ADHD Disappears along with Removal of Tonsils

Doctors don't order tonsillectomies for children as often as they used to, but the surgery makes some kids sleep and behave better, according to a University of Michigan study.


U-M's four-year study, published today in the journal Pediatrics, found half of children who suffered from hyperactivity and attention disorders before the surgery no longer had the condition a year afterward.

Researchers believe enlarged tonsils can cause sleep problems, and sleep problems can cause daytime behavior troubles.

While the study doesn't prove a tonsillectomy is a cure for attention deficit hyperactivity disorder, removing enlarged tonsils can eliminate the cause of behavior disorders for some, said Dr. Ronald Chervin, a University of Michigan sleep disorder researcher and author of the study.


Is the US on the Wrong Side of the Technology Gap?

Think of Benjamin Franklin flying a kite in a storm to prove his theory of electricity, Alexander Graham Bell's telephone, Thomas Edison's invention of the light bulb and the Wright brothers' first flight at Kitty Hawk.

Since the dawn of the industrial revolution, American scientists, engineers and entrepreneurs have been at the forefront of technology. They have led the world in the creation of new products, services and industries.

Is this all coming to an end?

A new report from Economic Strategy Institute highlights weaknesses America's high-tech economy.

Since 2002 the US has imported more high-tech goods and services than it has exported. Falling revenues are forcing many US telecom and technology companies to cut back on R&D spending or outsource research abroad.



From
Sundown Lounge No. 39


The Net: A Political Free-For_All

Associated Press 09:45 AM Mar, 27, 2006



The Federal Election Commission decided Monday that the nation's new campaign finance law will not apply to most political activity on the internet.

In a 6-0 vote, the commission decided to regulate only paid political ads placed on another person's website.

The decision means that bloggers and online publications will not be covered by provisions of the new election law. Internet bloggers and individuals will therefore be able to use the internet to attack or support federal candidates without running afoul of campaign spending and contribution limits.

"It's a win, win, win," Commissioner Ellen L. Weintraub said, adding that the rule would satisfy concerns of campaigns, individuals and the internet community about whether the campaign finance law applies to online political activity.

The commission was forced to act after a federal court ruled that the FEC must extend some of the campaign financial and spending limits to political activity on the internet.

The 2002 law requires that campaign ads for federal candidates be paid for with money regulated by the law, which limits contributions by individuals to $2,000 and bans union and corporation donations.

In its initial interpretation of the law in 2002, the FEC said no political activity on the internet was covered. But a federal court judge ruled in 2004 that the commission had to craft a new rule that at the very least covered paid political advertising on the internet.


The ruling, and the commission's decision not to appeal it, sparked fears among some internet users that the panel might adopt broader restrictions. But FEC Chairman Michael E. Toner said the new rules give a "categorical and unqualified" exemption for all individual and group political activity on the internet, except for paid advertising."

"The law was never intended to regulate private citizen communication on the internet," said Commission Vice Chairman Robert D. Lenhard. "I believe that we have achieved that goal today."

Commissioners said the new rule also specifically changes several other FEC regulations to make it clear that internet activity, such as blogging, e-mail communications and online publications, is not covered by the campaign law.

For example, the rule says individuals can use union or corporate computers or other electronic devices for political activity, as long they do it on their own time and are not coerced to engage in such activity by the union or corporation.

Bloggers would be entitled to the same exemption from the campaign finance law that newspapers and other traditional forms of media receive.

"There will be no second class citizens among members of the media," Toner said.



Brain Teasers, By Clive Thompson


A while ago, the science writer Steven Johnson was looking at an old IQ test known as the "Raven Progressive Matrices." Developed in the 1930s, it shows you a set of geometric shapes and challenges you to figure out the next one in the series. It's supposed to determine your ability to do abstract reasoning, but as Johnson looked at the little cubic Raven figures, he was struck by something: They looked like Tetris.

A light bulb went off. If Tetris looked precisely like an IQ test, then maybe playing Tetris would help you do better at intelligence tests. Johnson spun this conceit into his brilliant book of last year, Everything Bad Is Good For You, in which he argued that video games actually make gamers smarter. With their byzantine key commands, obtuse rule-sets and dynamic simulations of everything from water physics to social networks, Johnson argued, video games require so much cognitive activity that they turn us into Baby Einsteins -- not dull robots.

I loved the book, but it made me wonder: If games can inadvertently train your brain, why doesn't someone make a game that does so intentionally?

I should have patented the idea. Next month, Nintendo is releasing Brain Age, a DS game based on the research of the Japanese neuroscientist Ryuta Kawashima. Kawashima found that if you measured the brain activity of someone who was concentrating on a single, complex task -- like studying quantum theory -- several parts of that person's brain would light up. But if you asked them to answer a rapid-fire slew of tiny, simple problems -- like basic math questions -- her or his brain would light up everywhere.

Hence the design of Brain Age. It offers you nine different tests, some of which seem incredibly basic -- like answering flash-card math questions -- and others which are fiendishly tricky. At one point, the DS shows flashes a grid of numbers for one second, then hides the digits; you have to try to remember where they were located in the grid, in ascending order. After you've played a few rounds, the DS calculates your "brain age": How mentally nimble you are, compared to the statistical averages of other people Kawashima measured. Age 20 is the best you can do -- the apex of your mental powers, apparently -- and by playing Brain Age every day, you can become mentally younger and younger.

Now, the science here is a little dubious. The idea of a discrete brain age is about as phrenologically suspect as the increasingly-disputed concept of IQ itself. Kawashima believes you improve your cognition by getting your brain to light up all over at once. But not all neuroscientists agree that this full-brain activity means you're thinking more intelligently.

I'm quibbling, though. The truth is, scientists have long known that you can get smarter and stay smarter by engaging in daily, brain-teasing activity -- and Brain Age certainly qualifies.

Indeed, for something that doesn't even seem like normal "game," it's weirdly addictive. The math questions had me so frazzled that I emotionally regressed to about age ten. Brain Age also includes a Stroop test, which flashes the names of colors on screen in mismatched ink -- for example, the word "blue" printed in red -- and challenges you to name the color of the ink. As any psychologist will tell you, you can keep a lid on things for the first dozen words, but then your brain turns to jelly. My adrenaline was pumping harder than the first time I faced The Flood in Halo. Plus, when a game actually judges your intellect? Man, that hits home. After my first round, Brain Age claimed I possessed the mind of a 68-year-old, and I nearly wept. I frantically plinked away at math tests for two hours until I got my score down to 33.

I had much the same response to PQ: Practical Intelligence Quotient, another brain-training game released in December. It plays much more like a regular platform-puzzler: You control a little man who inhabits a Tron-like, glowing grid-world composed of cubes. You move cubes into various configurations, which purportedly tests your "planning ability"; meanwhile, you trip a series of switches to open doors, which flexes your logical thinking.

PQ is hard: It plays like the most hellish Tomb Raider level you ever encountered. Indeed, with its spare, geometric shapes, PQ feels like the ur-game that lurks inside all other games -- puzzle-solving boiled down to its Platonic essence. Strip away all the medieval garb, gibbering monsters and postapocalyptic dungeons from most RPGs and stealth games, and you'd have something that looks pretty much like PQ.

Which is precisely Steven Johnson's point. Beneath the surface of every game, there's a gymnasium for your mind.

It would be pretty hilarious if games took seriously their role as cognitive food, and, like boxes of cereal, began proclaiming their nutritional value: "This game will stimulate your prefrontal cortex 500 percent more than an episode of Everybody Loves Raymond and 75 percent more than reading The Washington Post!!" But of course, the very fact that we still ruminate on whether games make you smarter or dumber is a symptom of how games are still coming of age in our mediasphere. Nobody sits around debating whether the act of reading stimulates your mind, after all.

But if you'll excuse me now, I've got to get back to some mental exercise. By this time tomorrow, I should be 24 years old.





From Impact Lab: Paper Batteries

For applications that need only small amounts of power, here's a new idea - flexible paper batteries. These batteries use a paper layer containing the electrolyte as the separator between the anode and the cathode. They are easy and cheap to manufacture because they are produced using printing machines and environmentally friendly because of easy disposal. And as they're thin and flexible, they can be tailored for a large variety of applications, including cosmetics, smart cards, sensors, greeting cards or semi-active RFIDs [And better bugs for the NSA...Ed]




From Impact Lab: Body Implants as Fashion

Tatoos, body piercing, and even branding are so yesterday. The next wave to shock parents will be body implants. Caution, these are not for people with weak stomachs.

For those of you who want to stand out in a crowd, the bar has just been raised even further. There is something very painful and very disturbing about these photos.


From Geeknotes:

THE TIME INSIDE, an exhibition of video and photography by Luca Curci & Fabiana Roscioli

Opening: April 6 2006, 7 p.m. Dates: April 4 - 29, 2006
Location: Galerie Mamia Bretesché - 48, rue Chapon - Paris
contact. lucacurci@lucacurci.com




From
Sundown Lounge No. 38


It's Spring!


I looked up "Regeneration" in a search engine, and up popped the University of Michigan, whose scientists have received a $3-million, five-year grant from the National Institutes of Health to develop a new interdisciplinary program to train tomorrow's leaders in regenerative science.

Next, this article from Science:

What Controls Organ Regeneration?
R. John Davenport

Unlike automobiles, humans get along pretty well for most of their lives with their original parts. But organs do sometimes fail, and we can't go to the mechanic for an engine rebuild or a new water pump--at least not yet. Medicine has battled back many of the acute threats, such as infection, that curtailed human life in past centuries. Now, chronic illnesses and deteriorating organs pose the biggest drain on human health in industrialized nations, and they will only increase in importance as the population ages. Regenerative medicine--rebuilding organs and tissues--could conceivably be the 21st century equivalent of antibiotics in the 20th. Before that can happen, researchers must understand the signals that control regeneration.

Researchers have puzzled for centuries over how body parts replenish themselves. In the mid-1700s, for instance, Swiss researcher Abraham Trembley noted that when chopped into pieces, hydra--tubelike creatures with tentacles that live in fresh water--could grow back into complete, new organisms. Other scientists of the era examined the salamander's ability to replace a severed tail. And a century later, Thomas Hunt Morgan scrutinized planaria, flatworms that can regenerate even when whittled into 279 bits. But he decided that regeneration was an intractable problem and forsook planaria in favor of fruit flies.

Mainstream biology has followed in Morgan's wake, focusing on animals suitable for studying genetic and embryonic development. But some researchers have pressed on with studies of regeneration superstars, and they've devised innovative strategies to tackle the genetics of these organisms. These efforts and investigations of new regeneration models--such as zebrafish and special mouse lines--are beginning to reveal the forces that guide regeneration and those that prevent it.

Animals exploit three principal strategies to regenerate organs. First, working organ cells that normally don't divide can multiply and grow to replenish lost tissue, as occurs in injured salamander hearts. Second, specialized cells can undo their training--a process known as dedifferentiation--and assume a more pliable form that can replicate and later respecialize to reconstruct a missing part. Salamanders and newts take this approach to heal and rebuild a severed limb, as do zebrafish to mend clipped fins. Finally, pools of stem cells can step in to perform required renovations. Planaria tap into this resource when reconstructing themselves.

Humans already plug into these mechanisms to some degree. For instance, after surgical removal of part of a liver, healing signals tell remaining liver cells to resume growth and division to expand the organ back to its original size. Researchers have found that when properly enticed, some types of specialized human cells can revert to a more nascent state (see p. 85). And stem cells help replenish our blood, skin, and bones. So why do our hearts fill with scar tissue, our lenses cloud, and our brain cells perish? Animals such as salamanders and planaria regenerate tissues by rekindling genetic mechanisms that guide the patterning of body structures during embryonic development. We employ similar pathways to shape our parts as embryos, but over the course of evolution, humans may have lost the ability to tap into it as adults, perhaps because the cell division required for regeneration elevated the likelihood of cancer. And we may have evolved the capacity to heal wounds rapidly to repel infection, even though speeding the pace means more scarring. Regeneration pros such as salamanders heal wounds methodically and produce pristine tissue. Avoiding fibrotic tissue could mean the difference between regenerating and not: Mouse nerves grow vigorously if experimentally severed in a way that prevents scarring, but if a scar forms, nerves wither.

Unraveling the mysteries of regeneration will depend on understanding what separates our wound-healing process from that of animals that are able to regenerate. The difference might be subtle: Researchers have identified one strain of mice that seals up ear holes in weeks, whereas typical strains never do. A relatively modest number of genetic differences seems to underlie the effect. Perhaps altering a handful of genes would be enough to turn us into superhealers, too. But if scientists succeed in initiating the process in humans, new questions will emerge. What keeps regenerating cells from running amok? And what ensures that regenerated parts are the right size and shape, and in the right place and orientation? If researchers can solve these riddles--and it's a big "if"--people might be able to order up replacement parts for themselves, not just their '67 Mustangs.


New Crop - Wild Triga

Wild Triga is a perennial relative of wheat, and unlike wheat and other grains such as corn, rice, oats, barley and amaranth, triga does not have to be replanted each year. Instead this perennial plant provides cropland with a permanent cover while producing a new crop of grain every year. This protective blanket of vegetation not only protects the soil from erosion, it also provides habitat for wildlife and builds soil structure, increases organic matter, water infiltration and biological activity in the soil.

I have an introduction from the Rodale Institute, and a wild triga factsheet from Purdue University's Center for New Crops & Plant Products...

For urban green thumb folks, here's a webpage on Mini-farming and Mini-ranching...

Finally, "The Longevity Meme"...

Research undertaken in 2004 and 2005 suggests that adult stem cells - which become less effective at their job of repair and healing with age - could be rejuvenated, restored to action with the right biochemical cues. This exciting research offers additional opportunities for the use of stem cell research to extend healthy life span and the normal capabilities of a healthy adult.


From
Sundown Lounge No. 37




From Scientific American:
Nanofibers in Neurosurgery

Brain injuries afflict more than five million Americans, ranging from head trauma to stroke. Currently, there is no way to restore lost function or recapture what can be a profound shift in ability and even personality. But new research suggests that nanofibers can help induce neurons to reconnect and restore vision in the process, at least in hamsters.

A team of neuroscientists at the Massachusetts Institute of Technology and their colleagues at Hong Kong University purposefully wounded 53 newly born hamster pups. They cut a relatively deep gash--1.5 millimeters deep and two millimeters wide--through the optic tract in the brains of the young rodents. The wounds of 10 of the pups were then treated with 10 microliters of a solution composed of 99 percent water and 1 percent of a special ionic peptide. These short amino acids are capable of creating a molecular scaffold that can bridge such gaps...

Styrofoam-Eating Bacteria

Bacteria are everywhere, silently going about their business of breaking down cellulose, fermenting foods or fixing nitrogen in the soil, among a host of other activities. Given their ubiquity and diversity of functions, biotechnologists have been searching for new uses for different strains of the microscopic organisms, such as consuming oil spills or even capturing images. Now biologists at the University College Dublin in Ireland have found that a strain of Pseudomonas putida can exist quite happily on a diet of pure styrene oil--the oil remnant of superheated Styrofoam--and, in the process, turn the environmental problem into a useful, biodegradable plastic.

From Wired.com:
The Hunch Engine

It's the paradox of human-computer interaction. Computers can process huge numbers quickly and without bias, but programming them to detect faces, trees and puppies is incredibly difficult. Determining beautiful, pristine or cute is impossible.

People, on the other hand, are adept at recognizing patterns. Even newborn humans show a tendency to prefer human faces, demonstrating that the pattern-recognition part of us is deep and innate.

Now researchers are readying a new suite of tools that marry those two complementary skills, using software to enhance and refine human intuition. "The computers do the computer stuff, and the humans do the human stuff," says Eric Bonabeau, founder of Icosystem.

Bonabeau, a former researcher at the Santa Fe Institute, calls his innovation "the hunch engine." Presented to a general audience for the first time at the O'Reilly Emerging Technology Conference here, the engine is a technological implementation of the "obscenity principle" -- a user of the hunch engine may not know what they are looking for, but they will "know it when they see it," the test Supreme Court Justice Potter Stewart famously offered as a metric to define obscenity.

When the user starts the hunch engine he is presented with a seed -- a starting point -- and a set of mutations. The user selects mutations that look promising in his eyes, and the application uses that selection to generate another set of mutations, continuing in that fashion until the user is satisfied with what he sees.

Call it guided natural selection, where the selector for fitness is what looks good to the human in front of the monitor.

The Universe Is A Quantum Computer

Seth Lloyd is the kind of guy you'd like to have a beer with. Between gulps, the MIT prof will impart the details of how the universe really works. And if you order another, he'll give you a summary of one of the most mind-boggling ideas emerging in science today. His new book, Programming the Universe, is a plainspoken tale of how the universe is - tell me if you've heard this before - one very large quantum computer. - Kevin Kelly...

These items sent in by Manny, my Nigerian movie producer buddy...

Brainwashing Techniques

I'm Dick Sutphen and this tape is a studio-recorded, expanded version of a talk I delivered at the World Congress of Professional Hypnotists Convention in Las Vegas, Nevada. Although the tape carries a copyright to protect it from unlawful duplication for sale by other companies, in this case, I invite individuals to make copies and give them to friends or anyone in a position to communicate this information.

Although I've been interviewed about the subject on many local and regional radio and TV talk shows, large-scale mass communication appears to be blocked, since it could result in suspicion or investigation of the very media presenting it or the sponsors that support the media. Some government agencies do not want this information generally nown. Nor do the Born-Again Christian movement, cults, and many human-potential trainings.

Everything I will relate only exposes the surface of the problem. I don't know how the misuse of these techniques can be stopped. I don't think it is possible to legislate against that which often cannot be detected; and if those who legislate are using these techniques, there is little hope of affecting laws to govern usage. I do know that the first step to initiate change is to generate interest. In this case, that will probably only result from an underground effort. In talking about this subject, I am talking bout my own business. I know it, and I know how effective it can be. I produce hypnosis and subliminal apes and, in some of my seminars, I use conversion tactics to assist participants to become independent and self-sufficient. But, anytime I use these techniques, I point out that I am using them, and those attending have a choice to participate or not. They also know what the desired result of participation will be.

So, to begin, I want to state the most basic of all facts about brainwashing: IN THE ENTIRE HISTORY OF MAN, NO ONE HAS EVER BEEN BRAINWASHED AND REALIZED, OR BELIEVED, THAT HE HAD BEEN BRAINWASHED. Those who have been brainwashed will usually passionately defend their manipulators, claiming they have simply been "shown the light" . . . or have been transformed in miraculous ways.

Factual backup for "Fahrenheit 911" - Section Three

Section Three covers the facts in Fahrenheit 9/11 from Osama's relations with his family through Bush's military records and ends with Bush's business history, including Arbusto, Harken and the Carlyle Group.


From
Sundown Lounge No. 36


Jeb Corliss...


From Impact Lab:
Wing Suits

Jumping out of a plane without a parachute is not something we recommend but that's exactly what B.A.S.E. jumper Jeb Corliss has been doing to help pave the way for the world's first landing attempt without a parachute. Amazing photos.

Chinese-Only Internet

The Chinese government has announced plans to launch an alternate Internet root system with new Chinese character domains for dot-com and dot-net. This may mean that Chinese Internet users will no longer rely on ICANN, the U.S.-backed domain name administrator, and, as one commentator notes, could be the beginning of the end of the globally interoperable Internet...

Extraterrestrial Rain

There is a small bottle containing a red fluid on a shelf in Sheffield University's microbiology laboratory. The liquid looks cloudy and uninteresting. Yet, if one group of scientists is correct, the phial contains the first samples of extraterrestrial life isolated by researchers.

Inside the bottle are samples left over from one of the strangest incidents in recent meteorological history. On 25 July, 2001, blood-red rain fell over the Kerala district of western India. And these rain bursts continued for the next two months. All along the coast it rained crimson, turning local people's clothes pink, burning leaves on trees and falling as scarlet sheets at some points.

Investigations suggested the rain was red because winds had swept up dust from Arabia and dumped it on Kerala. But Godfrey Louis, a physicist at Mahatma Gandhi University in Kottayam, after gathering samples left over from the rains, concluded this was nonsense. 'If you look at these particles under a microscope, you can see they are not dust, they have a clear biological appearance...'


Smart Gardens

Something for you home gardeners - an automatic system intended for growing small- to medium-sized herbs and flowers without the complexity of a recirculating hydroponic system. It's called a Smart Garden. Just passing it on...

From Geeknotes:



Daize Shayne takes "First Place" in the Surfing Mag. Reader's Choice Poll for Hottest Surf Babe!!!

Go Daize...Go Daize...Go Daize...Go Daize!!!!

www.daize.com



Hi all. I have been posting new shows and adding videos. I'm going for a shorter (~5min) format as I'm being positioned for cell phone distribution (Yaaaaaa!!)

I'm planning to do 5 minute shows Mon-Thur and then a longer music focused show on Fridays. Whatta ya think?

I'm also inviting folks to call in their positive vibe tips and we'll play them on our show 206-888-Chick (2442).

Make'm Smile!

KFC


From
Sundown Lounge No. 35


this one costs $100...

From the Mount Washington Observatory: Storm Glass

While doing a 'weird science' search, I delved into chemistry, landing on the Darwin Expedition and came across an instrument I'd never heard of before - a storm glass.

Storm glasses are hermetically sealed glass tubes containing a supersaturated mixture of chemicals. The premise is that changing weather affects the solubility of the mixture. huh... Apparently, clear liquid meant bright weather; dim liquid, rain. Large flakes meant overcast or, in winter, snowy skies. As its name implies, many believed the instrument was especially sensitive to the coming of stormy weather. So, if small stars are seen in dim liquid, you expect thunderstorms.

The captain of the Beagle, Admiral Robert Fitzroy, invented this original barometer to forecast the weather. In 1863 he got the mixture right - distilled water, ethanol, potassium nitrate, ammonium chloride, and camphor.

There's a Wikipedia page on this instrument, and yes, you can buy 'em, but if you'd like to make your own, with this receipe (with the assistance of a chemistry geek buddy...)




Wilhelm Reich(1897-1957) was a psychoanalyst and student of Sigmund Freud, who pioneered the study of the orgasm and human sexuality. His book 'The Bion' (1938) extended the scope of Reich's research from bodywork and the bioelectric nature of pleasure and anxiety to consider a vast cosmology and the origins of life. Reich claimed to have discovered 'Orgone' ('Lifeforce'), and explored the implications in 'Bion Experiments and the Cancer Problem' (1939). In 1952 and 1953 Reich experimented with weather control and cloudbusting. Reich also developed a metal-lined device named the "Orgone Accumulator", believing that the box trapped orgone energy that he could harness in groundbreaking approaches towards psychiatry, medicine, the social sciences, biology and weather research. This is where the feds stepped in...

What is Orgone Energy?

How to build your own Orgone Accumulator





I don't have words to express the almost personal connection I felt as a reader of her works, or the loss I feel. There are many others who can speak more eloquently about her, and the Tuesday LA Times ran a long obit on her.


From
Sundown Lounge No. 34




From Scientific American: Mutant Chicken Teeth

Working late in the developmental biology lab one night, Matthew Harris of the University of Wisconsin noticed that the beak of a mutant chicken embryo he was examining had fallen off. Upon closer examination of the snubbed beak, he found tiny bumps and protuberances along its edge that looked like teeth--alligator teeth to be specific. The accidental discovery revealed that chickens retain the ability to grow teeth, even though birds lost this feature long ago. The finding also resurrected the controversial theory of one of the founders of comparative anatomy, Etienne Geoffroy Saint-Hillaire.

In the early 19th century, Saint-Hillaire observed that developing parrots have tiny bumps on their beaks that resemble teeth, something he ascribed to modern animals deriving from more basic primitive forms. But due to his developing battles with Georges Cuvier over evolution, the finding was forgotten until Harris, a graduate student, rediscovered it nearly 200 years later...




From Impact Lab: Energy From Dog Poop

San Francisco, a leader in urban recycling, is preparing to enlist its canine population for a first in the United States: converting dog poop into energy.

Norcal Waste Systems Inc., the city's garbage company, plans to test collection carts and biodegradable bags in a city-center park popular with dog walkers.

A city study found that almost 4 percent of all the garbage picked up at San Francisco homes was from animal waste destined for the city's landfill, Norcal Waste spokesman Robert Reid said. San Francisco has an estimated 120,000 dogs...


From
Sundown Lounge No. 33


Latest Cold Fusion News, From Scienceblog.com...

Researchers at Rensselaer Polytechnic Institute have developed a tabletop accelerator that produces nuclear fusion at room temperature, providing confirmation of an earlier experiment conducted at the University of California, Los Angeles (UCLA), while offering substantial improvements over the original design.

The device, which uses two opposing crystals to generate a powerful electric field, could potentially lead to a portable, battery-operated neutron generator for a variety of applications, from non-destructive testing to detecting explosives and scanning luggage at airports...


ROME (Reuters) - An Italian atheist lost his legal crusade against the Catholic Church on Thursday when a judge rejected his attempts to sue a priest for saying that Jesus existed 2,000 years ago, the priest's lawyer said.

Luigi Cascioli, 72, had argued his hometown priest and former schoolmate had effectively broken an Italian law meant to protect the public from being conned.

But instead of granting Cascioli his request to bring the case to court, the judge recommended magistrates investigate him for slandering priest Enrico Righi, Righi's lawyer, Bruno Severo said.

The 76-year-old priest said he was delighted by the news.

"Thank God it's over," Righi told Reuters. "I'm glad it has ended like this, because imagine if it had gone on and on."

Cascioli, author of a book called "The Fable of Christ", said the court had not yet informed him of the ruling. But he was not surprised, and said he would appeal to Italy's highest court, and then to The Hague.

Asked about the possibility he would be tried for slander, Cascioli chuckled, saying that to prove he lied, prosecutors would have to prove that Jesus existed.

"They don't have any proof," he said.


Soldiers Face Debilitating Diseases

They served their time in the military in places like Saudi Arabia and Kuwait, and more recently, Iraq and Afghanistan.

Most returned in good health.

But an NBC 30 (in Connecticut) investigation has found that for some soldiers, their service has meant a long and debilitating death sentence with mysterious diseases.

"I have good days, I have bad days," said M. Sterry, of New Haven. "There were eight of us that served together. Six of my friends are dead."

She looks healthy, but Sterry is a very sick woman who has no idea how much longer she will live.

"I've had three heart attacks, two heart surgeries. I have chronic headaches, chronic upper respiratory infections. I get pneumonia two or three times a year," she said. "I have chronic fatigue, joint aches, muscle aches. I have a rash that migrates all over my body."

Sterry figures the initial symptoms began in Saudi Arabia in September of 1991 while she was serving with the National Guard. Three years later, after completing her tour of duty and coming back home, the symptoms were still there, but much more severe.

State Sen. Gayle Slossberg said one of the sources of the diseases may be depleted uranium. She was one of those who helped pass legislation last year setting up a health registry in Connecticut, strictly to keep records on our military personnel.

"We'll know where they've served, what they've done, what the scope of the job was," she said. "We'll be able to identify to some extent what they've been exposed to and what their symptoms are."

But it will come too late for David Leighton, of Naugatuck, a Marine who served in Saudi Arabia in Desert Storm. When he came home, the symptoms he had had for quite some time would not go away.

His mother, Gail Leighton, said that for the next 15 years, she saw her once vital and vibrant son slowly dying before her eyes.

"You would have had to have been there during the journey and see him in bed and sweating and in agony," she said.

She said her son was a patriot, that his dad had been a Marine. She said the federal government did not believe that those coming back became sick because of the conditions in which they served.

"That was the hardest part, I think, more than anything, to have the DOD, the Department of Defense, and the VA spending so much time and energy trying to deny and discount and discredit some of the people who were doing research."

State Veterans Commissioner Linda Schwartz told NBC 30 that making the connection between battlefield exposures and diseases has been a long, ongoing process.

She said the use of depleted uranium has to be studied because, as she put it, we're sending our best people into battle and their well-being must be the top priority.


From
Sundown Lounge No. 32


Continuing the thread on alternative energy, here's a list of articles on cold fusion and sonofusion (fusion generated by sound waves, covered previously in SL 14) from freeenergynews.com




The U.S. Department of Energy (DOE) believes that biofuels—made from crops of native grasses, such as fast - growing switchgrass — could reduce the nation's dependence on foreign oil, curb emissions of the "greenhouse gas" carbon dioxide, and strengthen America's farm economy. The Biofuels Feedstock Development Program (BFDP) at DOE's Oak Ridge National Laboratory (ORNL), has assembled a team of scientists ranging from economists and energy analysts to plant physiologists and geneticists to lay the groundwork for this new source of renewable energy. Included are researchers at universities, other national laboratories, and agricultural research stations around the nation. Their goal, according to ORNL physiologist Sandy McLaughlin, who leads the switchgrass research effort, is nothing short of building the foundation for a biofuels industry that will make and market ethanol and other biofuels from switchgrass and at prices competitive with fossil fuels such as gasoline and diesel...


Hey, Attorney General, Tap This!

A recent New York Times story about the NSA domestic eavesdropping program included the photograph below (Mike Theiler/European Pressphoto Agency) of students protesting Attorney General Alberto Gonzales by turning their backs to him during his speech.



A reader has this information to add: The NYT left out a funny detail — the students had the words “Tap This” printed on their asses, so Gonzales could read it as he gave his speech. A couple dozen students participated in the protest and some clips were shown on CNN the day of the speech. Too bad they didn't have a more Wonkette appropriate slogan on their asses — I'm sure you know what I'm talking about!




From
Sundown Lounge No. 31


Cold Fusion, by Michelle Thaller, csmonitor.com

PASADENA, CALIF. – For the last few years, mentioning cold fusion around scientists (myself included) has been a little like mentioning Bigfoot or UFO sightings.

After the 1989 announcement of fusion in a bottle, so to speak, and the subsequent retraction, the whole idea of cold fusion seemed a bit beyond the pale. But that's all about to change.

A very reputable, very careful group of scientists at the University of Los Angeles (Brian Naranjo, Jim Gimzewski, Seth Putterman) has initiated a fusion reaction using a laboratory device that's not much bigger than a breadbox, and works at roughly room temperature. This time, it looks like the real thing...


Breaking the 2nd Law of Thermodynamics

In the December 15 issue of Nature, a team of US scientists reported a very interesting observation : that, under certain circumstances, liquids that are stirred together--like cream into a cup of black coffee--can be unstirred, with the particles of each fluid moving precisely back to their former positions, as if time had reversed.

The well-known 2nd law of thermodynamics essentially states that disorder increases. In the long term, this means that the universe will inevitably fall apart. In the short term, it means that phenomena like the stirring of coffee, billowing of smoke, flow of heat, the decay of body and buildings are all "irreversible". Remember though that the basic physics laws of the universe do not have the notion of 'irreversibility' included in them; They do not demand the 2nd law.

David J. Pine of New York University and Jerry P. Gollub of Haverford College in Pennsylvania showed with their device that there is a sharp transition between reversible and irreversible flows. Their device has two concentric cylinders with a gap of about a tenth of an inch wide in between them, which they filled up with a liquid (of the viscosity of honey) and hundreds of thousands of tiny beads (of the same density as the liquid). Because of having same density, the beads floated within the liquid without rising or falling. David and Jerry traced the motion of about 60 such beads which they dyed black...

Then they rotated the inner cylinder - dragging along the liquid and the beads - and then turned it back to its original position. When the amount of turning was small, the balls all returned to virtually the same positions from where they started. For a slightly greater degree of turning, then the balls started moving around ending up in a completely different formation.

Study of such complex phenomena is important not only for understanding limits and scope of a fundamental law of Physics but also for its application in manufacturing drugs, refining oil and getting an insight into the movement of the Earth's interior.




Watching the vast devastation of New Orleans and all those destroyed homes that need to be cleared so the people can get back in and get started, well it made me think of prefab homes that were really popular in the south and other places when i was a kid. So I checked out Modernist Prefab Houses, and found a fresh item at Impact Lab.

We're talking 21st century design, nothing tacky here. We have 10 companies in Acton, MA, Los Angeles, Minneapolis/St. Paul, New York City, San Francisco, and St. Louis.

In size you got studios up to 3 bedrooms with two floors, from 1400 to 2400 sq. ft. at an avg. of $130/S.F. So that's roughly 180,000 to 300,000. In today's market, that's not bad for a house that'll roll up in a couple flatbeds and go up in less than a week, ready to be hooked up to the grid. Especially since FEMA still won't release the thousands of emergency mobile homes that were collected for the victims...


SAN FRANCISCO - Google (Research) is getting lambasted online for its new policy of accommodating China's Internet-censorship rules. But with its new Chinese search engine, Google.cn, Google isn't living up to its reputation for technical wizardry. Paul Boutin points out on his blog that if you search for "Tiananmen," you get peaceful photos of the Beijing square -- but if you search for common misspellings like "Tienanmen," "Tianenmen," or "Tiananman," you get photos of tanks.

Let's keep this item below the radar so free thinking and searching citizens in China can use it...


Here's the info on chicagopoetry.com's top 10 for February & Poet of the Month, and the 5th Annual PSH Great Poetry Exchange...


Map Room Archives:

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